Bachelor of Science [B.S] [Mathematics with Finance] From University of Brighton

Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases. Polysialic acid is aberrantly re - expressed on the surface of many tumours, where i t plays a key role in diseases progression and metastasis. It is therefore an attractive anti - cancer target.

The The Polysialyltransferases as a Target in Metastatic Cancer project from University of Bradford will focus on the biological evaluation of potential polysialyltransferase inhibitors, utilising in vitro assays to assess compound i nhibition, and techniques to assess effects of compounds on cell adhesion, migration, and invasion.